| Synopsis |
Highlighting dynamic developments in polymer synthesis, this book focuses on the chemical techniques to synthesize and characterize biomedically relevant polymers and shows their application in biomedicine. An added emphasis deals with characterizing these polymers through structure verification., Highlighting dynamic developments in polymer synthesis, this book focuses on the chemical techniques to synthesize and characterize biomedically relevant polymers and macromolecules. * Aids researchers developing polymers and materials for biomedical applications * Describes biopolymers from a synthetic perspective, which other similar books do not do * Covers areas that include: cationically-charged macromolecules, pseudo-peptides, polydrugs and prodrugs, controlled radical polymerization, self-assembly, polycondensates, and polymers for surface modification, Among the most active fields in chemical research, biorelated polymers are intimately related to progress in medicine and pharmaceuticals. Biomedical and genetic advances continuously open new needs for structurally well-defined polymers that accommodate and enable the function of therapeutics, sensing molecules, and novel micro- and macro-scale prosthetics. Highlighting dynamic developments in polymer synthesis, Polymers for Biomedicine: Synthesis, Characterization, and Applications focuses on the chemical techniques to synthesize and characterize biomedically relevant polymers and macromolecules. The chapters feature authors representing the multidisciplinary and diverse nature of the research into biomedically relevant polymers. These contributions aid researchers developing polymers and materials for biomedical applications, describing biopolymers from a synthetic perspective. The coverage includes important areas like cationically-charged macromolecules, pseudo-peptides, polydrugs and prodrugs, controlled radical polymerization, self-assembly, polycondensates, and polymers for surface modification., Highlighting dynamic developments in polymer synthesis, this book focuses on the chemical techniques to synthesize and characterize biomedically relevant polymers and macromolecules. - Aids researchers developing polymers and materials for biomedical applications - Describes biopolymers from a synthetic perspective, which other similar books do not do - Covers areas that include: cationically-charged macromolecules, pseudo-peptides, polydrugs and prodrugs, controlled radical polymerization, self-assembly, polycondensates, and polymers for surface modification |
| Table Of Content |
List of Contributors ix Part I. Pseudo-Peptides, Polyamino acids and Polyoxazolines 1 Chapter 1 - Characterization of Polypeptides and Polypeptoides -Methods and Challenges 3 David Huesmann and Matthias Barz Chapter 2- Poly(2-Oxazoline): The structurally Diverse Biocompatibilizing Polymer 31 Rodolphe Obeid Chapter 3- Poly(2-oxazoline) Polymers - synthesis, characterization and Applications in Development of Therapeutics 51 Randall W. Moreadith and Tacey X. Viegas Chapter 4- Polypeptoid Polymers: Synthesis, Characterization and Properties 77 Brandon A. Chan, Sunting Xuan, Ang Li, Jessica M. Simpson and Donghui Zhang Part II - Advanced Polycondensates 121 Chapter 5 - Polyanhydrides: Synthesis and Characterization 123 Rohan Ghadi, Eameema Muntimadugu Wahid Khan and Abraham J. Domb Chapter 6 - New Routes to Tailor-Made Polyesters 149 Kazuki Fukushima and Tomoko Fujiwara Chapter 7 - Polyphosphoesters: An old biopolymer in a new light 191 Kristin N. Bauer, Hisaschi T.C. Tee, Evandro M. Alexandrino and Frederik R. Wurm Part III. Cationically Charged Macromolecules 243 Chapter 8 - Design and Synthesis of Amphiphilic Vinyl Copolymers with Antimicrobial Activity 245 Leanna L. Foster, Masato Mizutani, Yukari Oda, Edmund F. Palermo and Kenichi Kuroda Chapter 9 - Enhanced Polyethylenimine-Based Delivery of Nucleic Acids 273 Jeff Sparks, Tooba Anwer and Khursheed Anwer Chapter 10 - Cationic graft copolymers for DNA engineering 297 Atsushi Maruyama and Naohiko Shimada Part IV. Biorelated polymers by Controlled Radical Polymerization 313 Chapter 11 - Synthesis of (Bio)degradable Polymers by Controlled/"Living" Radical Polymerization 315 Shannon R. Woodruff and Nicolay V. Tsarevsky Part V. Polydrugs and Polyprodrugs 355 Chapter 12 - Polymerized drugs - a novel approach to controlled release systems 357 B. Demirdirek, J. J. Faig, R. Guliyev and K.E.Uhrich Chapter 13 - Structural design and synthesis of polymer prodrugs 391 Petr Chytil, Libor Kostka and Tomás Etrych Part VI. Biocompatibilization of Surfaces 421 Chapter 14 - Polymeric ultrathin films for surface modifications 423 Henning Menzel Chapter 15 - Surface Functionalization of Biomaterials by Poly(2-oxazoline)s 457 Giulia Morgese and Edmondo M. Benetti Chapter 16 - Biorelated polymer brushes by surface initiated reversible deactivation radical polymerization 487 Rueben Pfukwa, Lebohang Hlalele and Bert Klumperman Part VII. Self-assembled Structures and Formulations 525 Chapter 17 - Synthesis of amphiphilic invertible polymers for biomedical applications 527 A.M. Kohut, I.O. Hevus, S.A. Voronov and A.S. Voronov Chapter 18 - Bioadhesive Polymers for Drug Delivery 559 Eenko Larrañeta and Ryan F. Donnelly INDEX |
user71041670
This book is a must-have for researchers in biomedical polymers! It brilliantly covers synthesis, characterization, and applications with a strong focus on practical techniques. The synthetic perspective on biopolymers sets it apart, making complex topics accessible. Perfect for developing new materials, it dives deep into cationically-charged macromolecules and beyond. Highly recommended for anyone in the field—clear, insightful, and packed with cutting-edge knowledge.